- should be elevated
- couldn't be converted to 11-deoxycortisol
- characteristics of 21 hydroxylase deficiency
2. Serum ACTH-elevated
3. urine test
- presence of 17-ketosteroids(derived from androgens)
- 10-15 times normal-Guyton Phiology Textbook
3. Renal function, electrolyte
- may be associated with electrolyte and water disturbances
- for e.g: in this case ' It's a Boy'- salt-wasting
- hyponatreamia
- hyperkaleamia`
- metabolic acidosis (after birth, why?)
4. karyotyping (map out the genetic make up)
5. Pelvic or abdominal ultrasound scan
- to determine pelvic structures and the presence/absence of gonads
prepared by:
SRI MURNIATI ROSLI
references:
- Ambiguous Genitalia in the NewbornInitial Assessment and Investigation
http://www.adhb.govt.nz/newborn/Guidelines/Endocrine/AmbiguousGenitalia.htm - http://www.doh.gov.za/docs/factsheets/pharma/paediatric/edlpaed141-175.pdf
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